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Directing Traffic: How to effectively drive T cells into tumors

While immune checkpoint inhibitors (ICI) have demonstrated clinical activity in multiple tumor types, the majority of patients do not respond to ICI monotherapy. Mounting evidence suggests that ICI-mediated clinical responses rely upon tumor infiltration by T cells that are able to recognize and kil...

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Bibliografiske detaljer
Udgivet i:Cancer Discov
Main Authors: Anandappa, Annabelle J., Wu, Catherine J., Ott, Patrick A.
Format: Artigo
Sprog:Inglês
Udgivet: 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7007384/
https://ncbi.nlm.nih.gov/pubmed/31974169
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2159-8290.CD-19-0790
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