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Directing Traffic: How to effectively drive T cells into tumors

While immune checkpoint inhibitors (ICI) have demonstrated clinical activity in multiple tumor types, the majority of patients do not respond to ICI monotherapy. Mounting evidence suggests that ICI-mediated clinical responses rely upon tumor infiltration by T cells that are able to recognize and kil...

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Detalhes bibliográficos
Publicado no:Cancer Discov
Main Authors: Anandappa, Annabelle J., Wu, Catherine J., Ott, Patrick A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7007384/
https://ncbi.nlm.nih.gov/pubmed/31974169
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2159-8290.CD-19-0790
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