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km23-1/DYNLRB1 regulation of MEK/ERK signaling and R-Ras in invasive human colorectal cancer cells

We previously found that km23-1/DYNLRB1 is required for TGFβ production through Ras/ERK pathways in TGFβ-sensitive epithelial cells and in human colorectal cancer (CRC) cells. Here we demonstrate that km23-1/DYNLRB1 is required for MEK activation in human CRC cells, detected by km23-1/DYNLRB1-siRNA...

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Publicat a:Cell Biol Int
Autors principals: Raza, Asif, Pandey, Madhu S., Jin, Qunyan, Mulder, Kathleen M.
Format: Artigo
Idioma:Inglês
Publicat: 2020
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7007335/
https://ncbi.nlm.nih.gov/pubmed/31393067
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cbin.11215
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