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Stereoselective Syntheses of 3′-Hydroxyamino- and 3′-Methoxyamino-2′,3′-Dideoxynucleosides

[Image: see text] Aminonucleosides are used as key motifs in medicinal and bioconjugate chemistry; however, existing strategies toward 3′-hypernucleophilic amine systems do not readily deliver deoxyribo-configured products. We report diastereoselective syntheses of deoxyribo- and deoxyxylo-configure...

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Detalhes bibliográficos
Publicado no:Org Lett
Main Authors: Bose, Sritama, Hodgson, David R. W.
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2019
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7007280/
https://ncbi.nlm.nih.gov/pubmed/31668079
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.orglett.9b03474
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