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Understanding Ligand Binding Selectivity in a Prototypical GPCR Family
[Image: see text] Adenosine receptors are involved in many pathological conditions and are thus promising drug targets. However, developing drugs that target this GPCR subfamily is a challenging task. A number of drug candidates fail due to lack of selectivity which results in unwanted side effects....
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| Publicado no: | J Chem Inf Model |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Chemical
Society
2019
|
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7007187/ https://ncbi.nlm.nih.gov/pubmed/31125224 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jcim.9b00298 |
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