New Isatin–Indole Conjugates: Synthesis, Characterization, and a Plausible Mechanism of Their in vitro Antiproliferative Activity

BACKGROUND: Cancer remains the leading cause of human morbidity universally. Hence, we sought to assess the in vitro antiproliferative activity of new isatin-based conjugates (5a–s) against three human cancer cell lines. METHODS: The antiproliferative activities of compounds 5a–s were evaluated in v...

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Detalhes bibliográficos
Publicado no:Drug Des Devel Ther
Main Authors: Al-Wabli, Reem I, Almomen, Aliyah A, Almutairi, Maha S, Keeton, Adam B, Piazza, Gary A, Attia, Mohamed I
Formato: Artigo
Idioma:Inglês
Publicado em: Dove 2020
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7006853/
https://ncbi.nlm.nih.gov/pubmed/32099332
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S227862
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