Isatin-benzoazine molecular hybrids as potential antiproliferative agents: synthesis and in vitro pharmacological profiling

In continuation of our endeavor with respect to the development of potent and effective isatin-based anticancer agents, we adopted the molecular hybridization approach to design and synthesize four different sets of isatin-quinazoline (6a–f and 7a–e)/phthalazine (8a–f)/quinoxaline (9a–f) hybrids. Th...

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Vydáno v:Drug Des Devel Ther
Hlavní autoři: Abdel-Aziz, Hatem A, Eldehna, Wagdy M, Keeton, Adam B, Piazza, Gary A, Kadi, Adnan A, Attwa, Mohamed W, Abdelhameed, Ali S, Attia, Mohamed I
Médium: Artigo
Jazyk:Inglês
Vydáno: Dove Medical Press 2017
Témata:
Original Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5557401/
https://ncbi.nlm.nih.gov/pubmed/28848327
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S140164
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