Design, synthesis and α-glucosidase inhibition study of novel embelin derivatives

Embelin is a naturally occurring para-benzoquinone isolated from Embelia ribes (Burm. f.) of the Myrsinaceae family. It was first discovered to have potent inhibitory activity (IC(50) = 4.2 μM) against α-glucosidase in this study. Then, four series of novel embelin derivatives were designed, prepare...

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Bibliografiske detaljer
Udgivet i:J Enzyme Inhib Med Chem
Main Authors: Chen, Xiaole, Gao, Min, Jian, Rongchao, Hong, Weiqian David, Tang, Xiaowen, Li, Yuling, Zhao, Denggao, Zhang, Kun, Chen, Wenhua, Zheng, Xi, Sheng, Zhaojun, Wu, Panpan
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 2020
Fag:
Short Communication
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7006637/
https://ncbi.nlm.nih.gov/pubmed/31969031
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/14756366.2020.1715386
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