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Rapid, two-pot procedure for the synthesis of dihydropyridinones; total synthesis of aza-goniothalamin

A fast, protecting-group-free synthesis of dihydropyridinones has been developed. Starting from commercially available aldehydes, a novel one-pot amidoallylation gave access to diene compounds in good yields. Ring-closing metathesis conditions were then employed to produce the target dihydropyridino...

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Detalhes bibliográficos
Publicado no:Beilstein J Org Chem
Main Authors: Cogswell, Thomas J, Donald, Craig S, Marquez, Rodolfo
Formato: Artigo
Idioma:Inglês
Publicado em: Beilstein-Institut 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7006497/
https://ncbi.nlm.nih.gov/pubmed/32082432
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3762/bjoc.16.15
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