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Methods for the synthesis of polyhydroxylated piperidines by diastereoselective dihydroxylation: Exploitation in the two-directional synthesis of aza-C-linked disaccharide derivatives

BACKGROUND: Many polyhydroxylated piperidines are inhibitors of the oligosaccharide processing enzymes, glycosidases and glycosyltransferases. Aza-C-linked disaccharide mimetics are compounds in which saturated polyhydroxylated nitrogen and oxygen heterocycles are linked by an all-carbon tether. The...

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Bibliografiska uppgifter
Huvudupphovsmän: Kennedy, Andrew, Nelson, Adam, Perry, Alexis
Materialtyp: Artigo
Språk:Inglês
Publicerad: Beilstein-Institut 2005
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC1399450/
https://ncbi.nlm.nih.gov/pubmed/16542015
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1860-5397-1-2
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