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Tissue-specific autoimmunity controlled by Aire in thymic and peripheral tolerance mechanisms

Tissue-specific autoimmune diseases are assumed to arise through malfunction of two checkpoints for immune tolerance: defective elimination of autoreactive T cells in the thymus and activation of these T cells by corresponding autoantigens in the periphery. However, evidence for this model and the o...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Int Immunol
मुख्य लेखकों: Matsumoto, Minoru, Tsuneyama, Koichi, Morimoto, Junko, Hosomichi, Kazuyoshi, Matsumoto, Mitsuru, Nishijima, Hitoshi
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Oxford University Press 2019
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC7005526/
https://ncbi.nlm.nih.gov/pubmed/31586207
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/intimm/dxz066
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