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Digital PCR Assays for Precise Quantification of CD19-CAR-T Cells after Treatment with Axicabtagene Ciloleucel

Treatment with axicabtagene ciloleucel (Axi-cel) CD19-CAR-T (chimeric antigen receptor T) cells has been approved for refractory/relapsed diffuse large B cell lymphoma (DLBCL) and primary mediastinal large B cell lymphoma (PMBCL). Because treatment success as well as side effects might depend on CAR...

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Foilsithe in:Mol Ther Methods Clin Dev
Main Authors: Fehse, Boris, Badbaran, Anita, Berger, Carolina, Sonntag, Tanja, Riecken, Kristoffer, Geffken, Maria, Kröger, Nicolaus, Ayuk, Francis A.
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society of Gene & Cell Therapy 2020
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7005515/
https://ncbi.nlm.nih.gov/pubmed/32055645
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtm.2019.12.018
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