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Identifying multi-hit carcinogenic gene combinations: Scaling up a weighted set cover algorithm using compressed binary matrix representation on a GPU

Despite decades of research, effective treatments for most cancers remain elusive. One reason is that different instances of cancer result from different combinations of multiple genetic mutations (hits). Therefore, treatments that may be effective in some cases are not effective in others. We previ...

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Dettagli Bibliografici
Pubblicato in:Sci Rep
Autori principali: Al Hajri, Qais, Dash, Sajal, Feng, Wu-chun, Garner, Harold R., Anandakrishnan, Ramu
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7005272/
https://ncbi.nlm.nih.gov/pubmed/32029803
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-58785-y
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