טוען...
Estimating the number of genetic mutations (hits) required for carcinogenesis based on the distribution of somatic mutations
Individual instances of cancer are primarily a result of a combination of a small number of genetic mutations (hits). Knowing the number of such mutations is a prerequisite for identifying specific combinations of carcinogenic mutations and understanding the etiology of cancer. We present a mathemat...
שמור ב:
| הוצא לאור ב: | PLoS Comput Biol |
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| Main Authors: | , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
Public Library of Science
2019
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6424461/ https://ncbi.nlm.nih.gov/pubmed/30845172 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1006881 |
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