Systematic dissection of biases in whole-exome and whole-genome sequencing reveals major determinants of coding sequence coverage

Advantages and diagnostic effectiveness of the two most widely used resequencing approaches, whole exome (WES) and whole genome (WGS) sequencing, are often debated. WES dominated large-scale resequencing projects because of lower cost and easier data storage and processing. Rapid development of 3(rd...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Sci Rep
Hlavní autoři: Barbitoff, Yury A., Polev, Dmitrii E., Glotov, Andrey S., Serebryakova, Elena A., Shcherbakova, Irina V., Kiselev, Artem M., Kostareva, Anna A., Glotov, Oleg S., Predeus, Alexander V.
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2020
Témata:
Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7005158/
https://ncbi.nlm.nih.gov/pubmed/32029882
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-59026-y
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky