Quantification of T Cell Binding Polyclonal Rabbit Anti-thymocyte Globulin in Human Plasma with Liquid Chromatography Tandem-Mass Spectrometry

The addition of rabbit anti-human thymocyte globulin (ATG) to the conditioning regimen prior to allogeneic hematopoietic cell transplantation has significantly reduced the risk of graft-versus-host disease (GvHD) and graft failure. However, ATG has a small therapeutic window. Overexposure of ATG pos...

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Bibliographic Details
Published in:AAPS J
Main Authors: Amrani, Mohsin El, Admiraal, Rick, Willaert, Lobke, Ebskamp-van Raaij, Lysette J. C., Lacna, Amelia M., Hack, C. Erik, Huitema, Alwin D. R., Nierkens, Stefan, van Maarseveen, Erik M.
Format: Artigo
Language:Inglês
Published: Springer International Publishing 2020
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7005072/
https://ncbi.nlm.nih.gov/pubmed/32030538
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12248-020-0419-6
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