Optimal Mass Transport with Lagrangian Workflow Reveals Advective and Diffusion Driven Solute Transport in the Glymphatic System

The glymphatic system (GS) hypothesis states that advective driven cerebrospinal fluid (CSF) influx from the perivascular spaces into the interstitial fluid space rapidly transport solutes and clear waste from brain. However, the presence of advection in neuropil is contested and solutes are claimed...

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Veröffentlicht in:Sci Rep
Hauptverfasser: Kounda, Sunil, Elkin, Rena, Nadeem, Saad, Xue, Yuechuan, Constantinou, Stefan, Sanggaard, Simon, Liu, Xiaodan, Monte, Brittany, Xu, Feng, Van Nostrand, William, Nedergaard, Maiken, Lee, Hedok, Wardlaw, Joanna, Benveniste, Helene, Tannenbaum, Allen
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2020
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7004986/
https://ncbi.nlm.nih.gov/pubmed/32029859
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-59045-9
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