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Optimal Mass Transport with Lagrangian Workflow Reveals Advective and Diffusion Driven Solute Transport in the Glymphatic System

The glymphatic system (GS) hypothesis states that advective driven cerebrospinal fluid (CSF) influx from the perivascular spaces into the interstitial fluid space rapidly transport solutes and clear waste from brain. However, the presence of advection in neuropil is contested and solutes are claimed...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Kounda, Sunil, Elkin, Rena, Nadeem, Saad, Xue, Yuechuan, Constantinou, Stefan, Sanggaard, Simon, Liu, Xiaodan, Monte, Brittany, Xu, Feng, Van Nostrand, William, Nedergaard, Maiken, Lee, Hedok, Wardlaw, Joanna, Benveniste, Helene, Tannenbaum, Allen
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7004986/
https://ncbi.nlm.nih.gov/pubmed/32029859
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-59045-9
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