The nitrone spin trap 5,5-dimethyl-1-pyrroline N-oxide dampens lipopolysaccharide-induced transcriptomic changes in macrophages

M1-like inflammatory phenotype of macrophages plays a critical role in tissue damage in chronic inflammatory diseases. Previously, we found that the nitrone spin trap 5,5-dimethyl-1-pirroline N-oxide (DMPO) dampens lipopolysaccharide (LPS)-triggered inflammatory priming of RAW264.7 cells. Herein, we...

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Publicado en:Inflamm Res
Main Authors: Muñoz, MD, Della Vedova, MC, Bushel, PR, Ganini Da Silva, D, Mason, RP, Zhai, Z, Gomez-Mejiba, SE, Ramirez, DC
Formato: Artigo
Idioma:Inglês
Publicado: 2018
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7004658/
https://ncbi.nlm.nih.gov/pubmed/29589052
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00011-018-1141-z
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