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Modest Declines in Proteome Quality Impair Hematopoietic Stem Cell Self-Renewal
Low protein synthesis is a feature of somatic stem cells that promotes regeneration in multiple tissues. Modest increases in protein synthesis impair stem cell function, but the mechanisms by which this occurs are largely unknown. We determine that low protein synthesis within hematopoietic stem cel...
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| 出版年: | Cell Rep |
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| 主要な著者: | , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2020
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7004491/ https://ncbi.nlm.nih.gov/pubmed/31914399 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2019.12.003 |
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