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Burst and Tonic Spinal Cord Stimulation Both Activate Spinal GABAergic Mechanisms to Attenuate Pain in a Rat Model of Chronic Neuropathic Pain

BACKGROUND: Experimental and clinical studies have shown that tonic spinal cord stimulation (SCS) releases gamma‐aminobutyric acid (GABA) in the spinal dorsal horn. Recently, it was suggested that burst SCS does not act via spinal GABAergic mechanisms. Therefore, we studied spinal GABA release durin...

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Détails bibliographiques
Publié dans:Pain Pract
Auteurs principaux: Meuwissen, Koen P.V., de Vries, Luuk E., Gu, Jianwen Wendy, Zhang, Tianhe C., Joosten, Elbert A.J.
Format: Artigo
Langue:Inglês
Publié: John Wiley and Sons Inc. 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7004135/
https://ncbi.nlm.nih.gov/pubmed/31424152
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/papr.12831
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