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Burst and Tonic Spinal Cord Stimulation Both Activate Spinal GABAergic Mechanisms to Attenuate Pain in a Rat Model of Chronic Neuropathic Pain

BACKGROUND: Experimental and clinical studies have shown that tonic spinal cord stimulation (SCS) releases gamma‐aminobutyric acid (GABA) in the spinal dorsal horn. Recently, it was suggested that burst SCS does not act via spinal GABAergic mechanisms. Therefore, we studied spinal GABA release durin...

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Detalhes bibliográficos
Publicado no:Pain Pract
Main Authors: Meuwissen, Koen P.V., de Vries, Luuk E., Gu, Jianwen Wendy, Zhang, Tianhe C., Joosten, Elbert A.J.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7004135/
https://ncbi.nlm.nih.gov/pubmed/31424152
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/papr.12831
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