Intracranial antitumor activity with encorafenib plus binimetinib in patients with melanoma brain metastases: A case series

BACKGROUND: Sixty percent of patients with stage IV melanoma may develop brain metastases, which result in significantly increased morbidity and a poor overall prognosis. Phase 3 studies of melanoma usually exclude patients with untreated brain metastases; therefore, clinical data for intracranial r...

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Detalhes bibliográficos
Publicado no:Cancer
Main Authors: Holbrook, Kourtney, Lutzky, Jose, Davies, Michael A., Davis, Jessica Michaud, Glitza, Isabella C., Amaria, Rodabe N., Diab, Adi, Patel, Sapna P., Amin, Asim, Tawbi, Hussein
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
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Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7004095/
https://ncbi.nlm.nih.gov/pubmed/31658370
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cncr.32547
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