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Hyperglycemia aggravates acute liver injury by promoting liver‐resident macrophage NLRP3 inflammasome activation via the inhibition of AMPK/mTOR‐mediated autophagy induction

Although the detrimental effects of diabetes mellitus/hyperglycemia have been observed in many liver disease models, the function and mechanism of hyperglycemia regulating liver‐resident macrophages, Kupffer cells (KCs), in thioacetamide (TAA)‐induced liver injury remain largely unknown. In this stu...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Immunol Cell Biol
Egile Nagusiak: Wang, Qi, Wei, Song, Zhou, Shun, Qiu, Jiannan, Shi, Chenyu, Liu, Rui, Zhou, Haoming, Lu, Ling
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: John Wiley and Sons Inc. 2019
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7004066/
https://ncbi.nlm.nih.gov/pubmed/31625631
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imcb.12297
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