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Intercalation of a Heterocyclic Ligand between Quartets in a G‐Rich Tetrahelical Structure
YES G‐rich oligonucleotide VK2 folds into an AGCGA‐quadruplex tetrahelical structure distinct and significantly different from G‐quadruplexes, even though it contains four G(3) tracts. Herein, a bis‐quinolinium ligand 360A with high affinity for G‐quadruplex structures and selective telomerase inhib...
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| Publicado no: | Chemistry |
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| Principais autores: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7004031/ https://ncbi.nlm.nih.gov/pubmed/31750579 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/chem.201904923 |
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