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Coexistence of two main folded G-quadruplexes within a single G-rich domain in the EGFR promoter
EGFR is an oncogene which codifies for a tyrosine kinase receptor that represents an important target for anticancer therapy. Indeed, several human cancers showed an upregulation of the activity of this protein. The promoter of this gene contains some G-rich domains, thus representing a yet unexplor...
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| Pubblicato in: | Nucleic Acids Res |
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| Autori principali: | , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Oxford University Press
2017
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5737278/ https://ncbi.nlm.nih.gov/pubmed/28973461 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkx678 |
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