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Assisted delivery of anti-tumour platinum drugs using DNA-coiling gold nanoparticles bearing lumophores and intercalators: towards a new generation of multimodal nanocarriers with enhanced action

New gold and lipoic based nanocarriers for the delivery of platinum(ii) and platinum(iv) drugs are developed, which allow enhanced loading of the drug on the surface of the nanocarriers and release in a pH-dependent fashion, with superior release at lower pHs which are associated with many tumours....

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Detalhes bibliográficos
Publicado no:Chem Sci
Main Authors: Caballero, Ana B., Cardo, Lucia, Claire, Sunil, Craig, James S., Hodges, Nikolas J., Vladyka, Anton, Albrecht, Tim, Rochford, Luke A., Pikramenou, Zoe, Hannon, Michael J.
Formato: Artigo
Idioma:Inglês
Publicado em: Royal Society of Chemistry 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7003971/
https://ncbi.nlm.nih.gov/pubmed/32055309
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c9sc02640a
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