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Saturated oxygen and nitrogen heterocycles via oxidative coupling of alkyltrifluoroborates with alkenols, alkenoic acids and protected alkenylamines

Saturated heterocycles are important components of many bioactive compounds. The method disclosed herein enables a general route to a range of 5-, 6- and 7-membered oxygen and nitrogen heterocycles by coupling potassium alkyltrifluoroborates with heteroatom-tethered alkenes, predominantly styrenes,...

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Bibliografiske detaljer
Udgivet i:Chem Sci
Main Authors: Shikora, Jonathan M., Um, Chanchamnan, Khoder, Zainab M., Chemler, Sherry R.
Format: Artigo
Sprog:Inglês
Udgivet: Royal Society of Chemistry 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7003886/
https://ncbi.nlm.nih.gov/pubmed/32055311
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c9sc02835h
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