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Clinical utility of hereditary cancer panel testing: Impact of PALB2, ATM, CHEK2, NBN, BRIP1, RAD51C, and RAD51D results on patient management and adherence to provider recommendations

BACKGROUND: Although management guidelines exist for several genes associated with a 2‐fold to 5‐fold increase in the relative risk for certain cancers, the value of testing for them remains controversial. METHODS: De‐identified personal and family history data for 654 individuals with pathogenic va...

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Podrobná bibliografie
Vydáno v:Cancer
Hlavní autoři: Vysotskaia, Valentina, Kaseniit, K. Eerik, Bucheit, Leslie, Ready, Kaylene, Price, Kristin, Johansen Taber, Katherine
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7003834/
https://ncbi.nlm.nih.gov/pubmed/31682005
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cncr.32572
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