5,6,7,4’-Tetramethoxyflavanone protects against neuronal degeneration induced by dexamethasone by attenuating amyloidogenesis in mice

Long-term exposure to high glucocorticoid levels induces memory impairment and neurodegeneration in Alzheimer's disease (AD) by increasing the expression of amyloid β and tau hyperphosphorylation (pTau). Previous studies showed beneficial effects of flavonoids in neurodegenerative models. 5,6,7...

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Dettagli Bibliografici
Pubblicato in:EXCLI J
Autori principali: Pakdeepak, Kanet, Chokchaisiri, Ratchanaporn, Tocharus, Jiraporn, Jearjaroen, Pranglada, Tocharus, Chainarong, Suksamrarn, Apichart
Natura: Artigo
Lingua:Inglês
Pubblicazione: Leibniz Research Centre for Working Environment and Human Factors 2020
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Original Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7003641/
https://ncbi.nlm.nih.gov/pubmed/32038114
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.17179/excli2019-1940
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