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Cyanidin attenuates Aβ(25-35)-induced neuroinflammation by suppressing NF-κB activity downstream of TLR4/NOX4 in human neuroblastoma cells

Cyanidin is polyphenolic pigment found in plants. We have previously demonstrated that cyanidin protects nerve cells against Aβ(25-35)-induced toxicity by decreasing oxidative stress and attenuating apoptosis mediated by both the mitochondrial apoptotic pathway and the ER stress pathway. To further...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Acta Pharmacol Sin
Hauptverfasser: Thummayot, Sarinthorn, Tocharus, Chainarong, Jumnongprakhon, Pichaya, Suksamrarn, Apichart, Tocharus, Jiraporn
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6289386/
https://ncbi.nlm.nih.gov/pubmed/29671417
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2017.203
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