Whole-Genome Sequencing of Finnish Type 1 Diabetic Siblings Discordant for Kidney Disease Reveals DNA Variants associated with Diabetic Nephropathy

BACKGROUND: Several genetic susceptibility loci associated with diabetic nephropathy have been documented, but no causative variants implying novel pathogenetic mechanisms have been elucidated. METHODS: We carried out whole-genome sequencing of a discovery cohort of Finnish siblings with type 1 diab...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:J Am Soc Nephrol
Main Authors: Guo, Jing, Rackham, Owen J. L., Sandholm, Niina, He, Bing, Österholm, Anne-May, Valo, Erkka, Harjutsalo, Valma, Forsblom, Carol, Toppila, Iiro, Parkkonen, Maija, Li, Qibin, Zhu, Wenjuan, Harmston, Nathan, Chothani, Sonia, Öhman, Miina K., Eng, Eudora, Sun, Yang, Petretto, Enrico, Groop, Per-Henrik, Tryggvason, Karl
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Nephrology 2020
Assuntos:
Basic Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7003303/
https://ncbi.nlm.nih.gov/pubmed/31919106
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2019030289
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados