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Confirmation of GLRA3 as a susceptibility locus for albuminuria in Finnish patients with type 1 diabetes

Urinary albumin excretion is an early sign of diabetic kidney disease, affecting every third individual with diabetes. Despite substantial estimated heritability, only variants in the GLRA3 gene have been genome-wide significantly associated (p-value < 5 × 10(−8)) with diabetic albuminuria, in Fi...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Sandholm, Niina, Haukka, Jani K, Toppila, Iiro, Valo, Erkka, Harjutsalo, Valma, Forsblom, Carol, Groop, Per-Henrik
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6098108/
https://ncbi.nlm.nih.gov/pubmed/30120300
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-29211-1
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