The Establishment of Esophageal Precancerous Lesion Model by Using p53 Conditional Knockout Mouse in Esophageal Epithelium

Understanding the molecular mechanisms of precancerous lesion of esophageal cancer is beneficial for early diagnosis and early treatment. The deletion of p53 gene is common in esophageal cancer, but its pathogenesis is still unclear. An animal model is urgently needed to study the mechanisms of esop...

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Bibliographic Details
Published in:Biomed Res Int
Main Authors: Zhu, Lili, Xu, Yanyan, Chen, Xinhuan, Qin, Jiace, Niu, Tingting, Zhu, Yanyan, Jiang, Yanan, Zhao, Simin, Liu, Kangdong, Lu, Jing, Jin, Ge, Ma, Junfen, Dong, Ziming, Zhao, Jimin
Format: Artigo
Language:Inglês
Published: Hindawi 2020
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7003290/
https://ncbi.nlm.nih.gov/pubmed/32047812
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2020/4534289
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