Advances in Anti-Tumor Treatments Targeting the CD47/SIRPα Axis

CD47 is an immunoglobulin that is overexpressed on the surface of many types of cancer cells. CD47 forms a signaling complex with signal-regulatory protein α (SIRPα), enabling the escape of these cancer cells from macrophage-mediated phagocytosis. In recent years, CD47 has been shown to be highly ex...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Front Immunol
Prif Awduron: Zhang, Wenting, Huang, Qinghua, Xiao, Weiwei, Zhao, Yue, Pi, Jiang, Xu, Huan, Zhao, Hongxia, Xu, Junfa, Evans, Colin E., Jin, Hua
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Frontiers Media S.A. 2020
Pynciau:
Immunology
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7003246/
https://ncbi.nlm.nih.gov/pubmed/32082311
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.00018
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