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Advances in Anti-Tumor Treatments Targeting the CD47/SIRPα Axis
CD47 is an immunoglobulin that is overexpressed on the surface of many types of cancer cells. CD47 forms a signaling complex with signal-regulatory protein α (SIRPα), enabling the escape of these cancer cells from macrophage-mediated phagocytosis. In recent years, CD47 has been shown to be highly ex...
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| Publicado en: | Front Immunol |
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| Autores principales: | , , , , , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Frontiers Media S.A.
2020
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7003246/ https://ncbi.nlm.nih.gov/pubmed/32082311 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.00018 |
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