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Stress Resistance Screen in a Human Primary Cell Line Identifies Small Molecules That Affect Aging Pathways and Extend Caenorhabditis elegans’ Lifespan

Increased resistance to environmental stress at the cellular level is correlated with the longevity of long-lived mutants and wild-animal species. Moreover, in experimental organisms, screens for increased stress resistance have yielded mutants that are long-lived. To find entry points for small mol...

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Detalhes bibliográficos
Publicado no:G3 (Bethesda)
Principais autores: Zhang, Peichuan, Zhai, Yuying, Cregg, James, Ang, Kenny Kean-Hooi, Arkin, Michelle, Kenyon, Cynthia
Formato: Artigo
Idioma:Inglês
Publicado em: Genetics Society of America 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7003076/
https://ncbi.nlm.nih.gov/pubmed/31879284
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/g3.119.400618
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