Synaptotagmin-1 and Doc2b Exhibit Distinct Membrane-Remodeling Mechanisms

Synaptotagmin-1 (Syt1) is a calcium sensor protein that is critical for neurotransmission and is therefore extensively studied. Here, we use pairs of optically trapped beads coated with SNARE-free synthetic membranes to investigate Syt1-induced membrane remodeling. This activity is compared with tha...

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Detalhes bibliográficos
Publicado no:Biophys J
Main Authors: Sorkin, Raya, Marchetti, Margherita, Logtenberg, Emma, Piontek, Melissa C., Kerklingh, Emma, Brand, Guy, Voleti, Rashmi, Rizo, Josep, Roos, Wouter H., Groffen, Alexander J., Wuite, Gijs J.L.
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2020
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7002981/
https://ncbi.nlm.nih.gov/pubmed/31952804
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2019.12.021
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