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Liquid-Liquid Phase Separation of Histone Proteins in Cells: Role in Chromatin Organization
Liquid-liquid phase separation (LLPS) of proteins and nucleic acids has emerged as an important phenomenon in membraneless intracellular organization. We demonstrate that the linker histone H1 condenses into liquid-like droplets in the nuclei of HeLa cells. The droplets, observed during the interpha...
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| 出版年: | Biophys J |
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| 主要な著者: | , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
The Biophysical Society
2020
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7002979/ https://ncbi.nlm.nih.gov/pubmed/31952807 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2019.12.022 |
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