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Liquid-Liquid Phase Separation of Histone Proteins in Cells: Role in Chromatin Organization
Liquid-liquid phase separation (LLPS) of proteins and nucleic acids has emerged as an important phenomenon in membraneless intracellular organization. We demonstrate that the linker histone H1 condenses into liquid-like droplets in the nuclei of HeLa cells. The droplets, observed during the interpha...
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| Publicado no: | Biophys J |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Biophysical Society
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7002979/ https://ncbi.nlm.nih.gov/pubmed/31952807 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2019.12.022 |
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