Histone demethylase KDM5C is a SAHA-sensitive central hub at the crossroads of transcriptional axes involved in multiple neurodevelopmental disorders

A disproportional large number of neurodevelopmental disorders (NDDs) is caused by variants in genes encoding transcription factors and chromatin modifiers. However, the functional interactions between the corresponding proteins are only partly known. Here, we show that KDM5C, encoding a H3K4 demeth...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Hum Mol Genet
Main Authors: Poeta, Loredana, Padula, Agnese, Attianese, Benedetta, Valentino, Mariaelena, Verrillo, Lucia, Filosa, Stefania, Shoubridge, Cheryl, Barra, Adriano, Schwartz, Charles E, Christensen, Jesper, van Bokhoven, Hans, Helin, Kristian, Lioi, Maria Brigida, Collombat, Patrick, Gecz, Jozef, Altucci, Lucia, Di Schiavi, Elia, Miano, Maria Giuseppina
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2019
Assuntos:
General Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7002875/
https://ncbi.nlm.nih.gov/pubmed/31691806
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddz254
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados