Histone demethylase KDM5C is a SAHA-sensitive central hub at the crossroads of transcriptional axes involved in multiple neurodevelopmental disorders

A disproportional large number of neurodevelopmental disorders (NDDs) is caused by variants in genes encoding transcription factors and chromatin modifiers. However, the functional interactions between the corresponding proteins are only partly known. Here, we show that KDM5C, encoding a H3K4 demeth...

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Xehetasun bibliografikoak
Argitaratua izan da:Hum Mol Genet
Egile Nagusiak: Poeta, Loredana, Padula, Agnese, Attianese, Benedetta, Valentino, Mariaelena, Verrillo, Lucia, Filosa, Stefania, Shoubridge, Cheryl, Barra, Adriano, Schwartz, Charles E, Christensen, Jesper, van Bokhoven, Hans, Helin, Kristian, Lioi, Maria Brigida, Collombat, Patrick, Gecz, Jozef, Altucci, Lucia, Di Schiavi, Elia, Miano, Maria Giuseppina
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Oxford University Press 2019
Gaiak:
General Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7002875/
https://ncbi.nlm.nih.gov/pubmed/31691806
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddz254
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