Effects of Rikkunshito treatment on renal fibrosis/inflammation and body weight reduction in a unilateral ureteral obstruction model in mice

Chronic kidney disease (CKD) progresses to end-stage renal failure via renal tubulointerstitial fibrosis. Malnutrition, inflammation, and arteriosclerosis interact to exacerbate the poor prognosis of CKD, and their effective management is thus essential. The traditional Japanese medicine Rikkunshito...

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Udgivet i:Sci Rep
Main Authors: Wakui, Hiromichi, Yamaji, Takahiro, Azushima, Kengo, Uneda, Kazushi, Haruhara, Kotaro, Nakamura, Akiko, Ohki, Kohji, Kinguchi, Sho, Kobayashi, Ryu, Urate, Shingo, Suzuki, Toru, Kamimura, Daisuke, Minegishi, Shintaro, Ishigami, Tomoaki, Kanaoka, Tomohiko, Matsuo, Kohei, Miyazaki, Tomoyuki, Fujikawa, Tetsuya, Yamashita, Akio, Tamura, Kouichi
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7002622/
https://ncbi.nlm.nih.gov/pubmed/32024850
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-58214-0
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