Biologically Aggressive Phenotype and Anti-cancer Immunity Counterbalance in Breast Cancer with High Mutation Rate

While cancer cells gain aggressiveness by mutations, abundant mutations release neoantigens, attracting anti-cancer immune cells. We hypothesized that in breast cancer (BC), where mutation is less common, tumors with high mutation rates demonstrate aggressive phenotypes and attract immune cells simu...

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Veröffentlicht in:Sci Rep
Hauptverfasser: Takahashi, Hideo, Asaoka, Mariko, Yan, Li, Rashid, Omar M., Oshi, Masanori, Ishikawa, Takashi, Nagahashi, Masayuki, Takabe, Kazuaki
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2020
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7002588/
https://ncbi.nlm.nih.gov/pubmed/32024876
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-58995-4
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