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The E2F Pathway Score as a Predictive Biomarker of Response to Neoadjuvant Therapy in ER+/HER2− Breast Cancer

E2F transcription factors play critical roles in the cell cycle. Therefore, their activity is expected to reflect tumor aggressiveness and responsiveness to therapy. We scored 3905 tumors of nine breast cancer cohorts for this activity based on their gene expression for the Hallmark E2F targets gene...

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Bibliografski detalji
Izdano u:Cells
Glavni autori: Oshi, Masanori, Takahashi, Hideo, Tokumaru, Yoshihisa, Yan, Li, Rashid, Omar M., Nagahashi, Masayuki, Matsuyama, Ryusei, Endo, Itaru, Takabe, Kazuaki
Format: Artigo
Jezik:Inglês
Izdano: MDPI 2020
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7407968/
https://ncbi.nlm.nih.gov/pubmed/32650578
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells9071643
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