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Effect of hyperglycemia and rosiglitazone on renal and urinary neprilysin in db/db diabetic mice

Alteration in renin‐angiotensin system (RAS) has been implicated in the pathophysiology of diabetic kidney disease (DKD). The deleterious actions of angiotensin II (Ang II) could be antagonized by the formation of Ang‐(1–7), generated by the actions of angiotensin‐converting enzyme 2 (ACE2) and nepr...

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Detalhes bibliográficos
Publicado no:Physiol Rep
Principais autores: Alawi, Laale F., Emberesh, Sana E., Owuor, Brenda A., Chodavarapu, Harshita, Fadnavis, Rucha, El‐Amouri, Salim S., Elased, Khalid M.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7002536/
https://ncbi.nlm.nih.gov/pubmed/32026607
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14814/phy2.14364
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