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Novel pleconaril derivatives: influence of substituents in the isoxazole and phenyl rings on the antiviral activity against enteroviruses

Today, there are no medicines to treat enterovirus and rhinovirus infections. In the present study, a series of novel pleconaril derivatives with substitutions in the isoxazole and phenyl rings was synthesized and evaluated for their antiviral activity against a panel of pleconaril-sensitive and -re...

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Detalhes bibliográficos
Publicado no:Eur J Med Chem
Main Authors: Egorova, Anna, Kazakova, Elena, Jahn, Birgit, Ekins, Sean, Makarov, Vadim, Schmidtke, Michaela
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7002245/
https://ncbi.nlm.nih.gov/pubmed/31881489
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejmech.2019.112007
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