A study of Caenorhabditis elegans DAF-2 mutants by metabolomics and differential correlation networks

daf-2 is one of the most studied mutants in C.elegans: it contains a deletion in the gene orthologue of the insulin/insulin-like growth factor (IGF) receptor. Using high resolution (1)H NMR spectroscopy, metabolomics has helped to dissect the metabolic consequences of altered daf-2 signalling. Here,...

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Udgivet i:Mol Biosyst
Main Authors: Castro, Cecilia, Krumsiek, Jan, Lehrbach, Nicolas J., Murfitt, Steven A., Miska, Eric A., Griffin, Julian L
Format: Artigo
Sprog:Inglês
Udgivet: 2013
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7002165/
https://ncbi.nlm.nih.gov/pubmed/23475189
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c3mb25539e
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