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Integrating CRISPR Engineering and hiPSC-Derived 2D Disease Modeling Systems

Human induced pluripotent stem cells (hiPSCs) have revolutionized research on human diseases, particularly neurodegenerative and psychiatric disorders, making it possible to study mechanisms of disease risk and initiation in otherwise inaccessible patient-specific cells. Today, the integration of CR...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Neurosci
Prif Awduron: Rehbach, Kristina, Fernando, Michael B., Brennand, Kristen J.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Society for Neuroscience 2020
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7002154/
https://ncbi.nlm.nih.gov/pubmed/32024766
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0518-19.2019
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