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Integration of CRISPR-engineering and hiPSC-based models of psychiatric genomics
Neuropsychiatric disorders are highly heritable polygenic disorders arising from the complex interplay of highly penetrant rare variants and common variants of small effect. There is a large index of comorbidity and shared genetic risk between disorders, reflecting the pleiotropy of individual varia...
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| 出版年: | Mol Cell Neurosci |
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| 主要な著者: | , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2020
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7484226/ https://ncbi.nlm.nih.gov/pubmed/32712198 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mcn.2020.103532 |
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