Hyaluronan deposition in islets may precede and direct the location of islet immune-cell infiltrates

AIMS/HYPOTHESIS: Substantial deposition of the extracellular matrix component hyaluronan (HA) is characteristic of insulitis in overt type 1 diabetes. We investigated whether HA accumulation is detectable in islets early in disease pathogenesis and how this affects the development of insulitis and b...

Full beskrivning

Sparad:
Bibliografiska uppgifter
I publikationen:Diabetologia
Huvudupphovsmän: Bogdani, Marika, Speake, Cate, Dufort, Mathew J., Johnson, Pamela Y., Larmore, Megan J., Day, Anthony J., Wight, Thomas N., Lernmark, Åke, Greenbaum, Carla J.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2020
Ämnen:
Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7002022/
https://ncbi.nlm.nih.gov/pubmed/31907557
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00125-019-05066-7
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!

Liknande verk