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Optogenetics reveals Cdc42 local activation by scaffold-mediated positive feedback and Ras GTPase
Local activity of the small GTPase Cdc42 is critical for cell polarization. Whereas scaffold-mediated positive feedback was proposed to break symmetry of budding yeast cells and produce a single zone of Cdc42 activity, the existence of similar regulation has not been probed in other organisms. Here,...
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| Veröffentlicht in: | PLoS Biol |
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| Hauptverfasser: | , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Public Library of Science
2020
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7002011/ https://ncbi.nlm.nih.gov/pubmed/31978045 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.3000600 |
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